Serodiagnosis of parasitic diseases.

Biological and Immunological Reactions in Parasitic Diseases

Processed antigen reacts selectively with lymphocytes bearing .appropriate surface immunoglobulin molecules resulting in the clonal proliferation of these cells, produc­ing circulating immunoglobulin (humoral immunity) or non-circulating immunoglobulins (cellular immunity).  High levels of circulating immunoglobulins (lgM & lgG) occur in protozoa and helminths infections. Reaginic antibodies a...

Antigen microarrays for serodiagnosis of infectious diseases.

BACKGROUND Progress in robotic printing technology has allowed the development of high-density nucleic acid and protein arrays that have increased the throughput of a variety of assays. We generated protein microarrays by printing microbial antigens to simultaneously determine in human sera antibodies directed against Toxoplasma gondii, rubella virus, cytomegalovirus (CMV), and herpes simplex v...

Tropical Parasitic Lung Diseases

Protozoa and helminthes can affect the lung as a primary site, or a complication. Some parasites have a migration cycle through the lung (larva migrans), inducing blood and tissue eosinophilia. Clinical manifestations of lung involvement could be acute: asthma –like syndrome, or Loeffler’s syndrome, with dyspnea, wheezing, cough; or chronic such as hemoptysis or right heart failure signs. Acute...

The First National Congress of Parasitic Diseases and Zoonotic Parasites

Parasitic diseases of the heart.

The following chapter is one of a series of chapters in the volume entitled Infections of the Myocardium appearing in Frontiers in Bioscience. The full table of contents can be found at http://www.bioscience.org/current/special/tanowitz.htm. In this chapter, we review several parasitic infections involving the myocardium and pericardium. The most widely studied parasitic infection affecting the...